Professional Interests
Recent advances in pharmaceutical development and the molecular foundation of disease has translated into new therapeutic agents. We aim to apply our knowledge base in biomaterials, cellular biology, immunology and transport phenomena to develop novel therapeutics that take advantage of these advances. In the Ainslie lab we develop platforms through the applications of techniques like microfabrication and other common polymer chemistry methods. Our focus is to not only release doses of pharmaceuticals, but also use pharmaceuticals to skew the immune response of the body to act therapeutically.
Recent Publications
- Kauffman, KJ; Do, C; Sharma, S; Gallovic, MD; Bachelder, EM; Ainslie, KM. Synthesis and characterization of acetalated dextran polymer and microparticles with ethanol as a degradation product. ACS applied materials & interfaces. 2012 Aug 22;4(8):4149-55
- Kanthamneni, N; Sharma, S; Meenach, SA; Billet, B; Zhao, JC; Bachelder, EM; Ainslie, KM. Enhanced stability of horseradish peroxidase encapsulated in acetalated dextran microparticles stored outside cold chain conditions. International journal of pharmaceutics. 2012 Jul 15;431(1-2):101-10
- Meenach, SA; Kim, YJ; Kauffman, KJ; Kanthamneni, N; Bachelder, EM; Ainslie, KM. Synthesis, optimization, and characterization of camptothecin-loaded acetalated dextran porous microparticles for pulmonary delivery. Molecular pharmaceutics. 2012 Feb 6;9(2):290-8
- Kauffman, KJ; Kanthamneni, N; Meenach, SA; Pierson, BC; Bachelder, EM; Ainslie, KM. Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression. International journal of pharmaceutics. 2012 Jan 17;422(1-2):356-63
Honors
- 2009 Controlled Release Society Outstanding Oral Drug Delivery Award
- 2007 Controlled Release Society-Capsugel Post-Doc Award for Innovative Aspects of Oral Drug Delivery & Absorption
- 2004-2005 Walter R. and Aura Lee Supina Graduate Fellowship in Chemical Engineering
- 2000 The Pennsylvania State University Life Science Consortium Graduate Fellowship
Education
- Ph.D., 2005, The Pennsylvania State University, Chemical Engineering
- M.S., 2003, The Pennsylvania State University, Chemical Engineering
- B.S., 1999, Michigan State University, Chemical Engineering
